Hatice Neval Ertürk

Neval Ertürk is an award-winning teacher and scholar.  In recognition of her teaching and research with the undergraduate students at Converse, 她于2008年获得南卡罗来纳州独立学院和大学(SCICU)卓越教学奖.  2012年，她因“站在指导学生研究的最前沿”以及她为当地高中生开展的STEM外展活动而获得了Converse颁发的学术和创意成就奖，其中许多活动为学生带来了国家奖项. She was also a recipient of the 2012 Student Service: Above and Beyond Award for her service to students.

At Converse, Dr. Ertürk teaches a wide variety of courses in biology including Genetics, Cell Biology, Research Methods in Biology, Molecular Biology of the Cell, Forensic Genetics, Science and Gender and introductory biology courses. She believes research complements teaching, thus she regularly works with students on original research. 她还积极倡导在高中生中推广科学，并担任STEM劳动力的专业发展助理.

When not teaching or researching, she spends her time traveling, reading, watching science fiction movies and exploring nature.

Curriculum Vitae

Read more about Dr. Ertürk’s activities and accomplishments:

• Neval Erturk Ph.D.

Scholarly & Research Activity

Dr. ert rk是南卡罗来纳州机构间研究计划的积极参与者.  她担任南卡罗来纳州北部研究研讨会学生奖委员会主席, Review Board of SCICU Faculty Sponsored Research Program, and Science Review Committee of Piedmont III Region Science Fair.  In 2013, 她被选为英特尔国际科学与工程博览会的顾问委员会成员，任期三年.  2012年，她获得了南卡罗来纳州北部研究研讨会颁发的表彰奖章，以支持该州北部教师和学生的研究和学术努力。2011年，她获得了南卡罗来纳州科学院颁发的表彰证书，以表彰她在南卡罗来纳州支持和发展人才和研究方面的卓越表现.  She was also nominated to The Governor’s Award for Excellence in Science Outreach in 2010.

An active scholar, Dr. ert rk与她的学生和STEM工作人员的研究万博下载ios获得了国家和地区各级各机构的大量资助和奖励.  她是美国科学促进会(AAAS)专业会员, American Society for Plant Biologist (ASPB), Association of Southeastern Biologists (ASB), Council of Undergraduate Researchers (CUR), Association for Women in Science (AWIS), Association of College and University Biology Educators (ACUBE), Mentor Net, and Earthwatch Institute.

Publications & Presentations

• Alscher, R. G., Erturk, N. and Heath, L. S. (2002). 植物中的抗氧化剂和活性氧:超氧化物歧化酶(sod)在控制植物氧化应激中的作用. Journal of Experimental Botany, 53(372), 1331-1341.
• Erturk, H.N. and Esen, A. (1995). A b-glucosidase aggregating factor (BGAF) is present in “null” genotypes of maize. Maize Genetics Newsletters,69:25-26.
• Erturk, H.N. and Unlu, H. (1991). 由一种有机磷杀虫剂敌敌畏(DDVP)引起的表型异常 Drosophila melanogaster.  Doga-Tr. Journal of Zoology, 15:76-83.
• Erturk, H.N. and Unlu, H. (1991). The effects of dichlorvos (DDVP), on crossing-over in Drosophila melanogaster.  Doga-Tr. Journal of Biology, 15:139-143.
• Unlu, H. and Erturk, H.N. (1991). The effects of dichlorvos (DDVP), on sex-ratio in Drosophila melanogaster.  Doga-Tr. Journal of Zoology, 15:177-184.

INBRE Abstract

Investigation of Aryl Hydrocarbon Receptor Antagonistic Effects of Ganoderma lucidum

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor. It regulates the responses of the cell to a variety of polyaromatic hydrocarbons (PAH). AhR介导的对这些化学物质的毒性与多种病理条件有关, including cancer. Therefore AhR modulation currently is studied as an important physiological process. Reishi (Ganoderma lucidum), 冬虫夏草(冬虫夏草)和山楂(山楂)在中医中常用来治疗糖尿病等疾病, hypertension, and cancer as well as strengthening immune system. 先前，使用这三种补充剂产生的关联草药被报道为AhR拮抗剂，导致TCDD处理的细胞中Cyp1A1投影减少. 本研究的目的是确定作为AhR拮抗剂的补充剂. Real-time RT-PCR将用于检测MCF-7细胞中CYP1A1基因的表达,3,7,8-Tetrachlorodibenzodioxin (TCDD).

Investigation of cancer-selective apoptotic effects of Ganoderma lucidum

人们对使用草药替代传统疗法的兴趣已经存在了数百年. Ganoderma lucidum, commonly known as reishi, 蘑菇提取物是用来治疗各种症状和疾病的传统草药吗. Deemed “the mushroom of immortality” in China, it has been reported to help circulation and blood pressure, assist in regulation of the immune system, and most notably, suppress cancerous tumors. (1)它被认为是一种有效的癌症生长的补充和替代药物(CAM), especially when used in conjunction with other types of conventional treatment. Reishi is currently known to cause apoptosis in cancer cells, but the mechanisms by which the apoptosis occur has not been identified. The primary mechanism of apoptosis is caspase dependent. Caspases, or cysteine-aspartic proteases, 在程序性细胞死亡过程中，是否有一组蛋白酶在细胞部分的受控破坏中起主要作用. Caspase依赖性凋亡可由内在或外在机制触发. 内在机制由Caspase-8调节，外在机制由Caspase-9酶调节(2)。. 本研究的目的是探讨灵芝引发癌细胞凋亡的机制类型, and if it also triggers apoptosis in noncancerous cells as well. 了解细胞凋亡是由内在的还是外在的机制引起的是很重要的, 因为知道哪一种途径导致了细胞凋亡的作用，可以让我们更好地理解灵芝是如何以及为什么专门针对癌细胞的，并有助于确定灵芝的药物潜力.

Genetoxicity Preventative Effects of Ganoderma lucidum (reishi), Cordyceps sinensis (Cordyceps) andCrataegus monogyna (hawthorn) in Rats

阿育吠陀和传统中医等医学实践使用植物产品混合物, called associations, in order to maximize the therapeutic benefits of these supplements. 一种市售的关联物及其单独的化合物灵芝(灵芝), 冬虫夏草(c)和山楂(山楂)因其抗肿瘤和免疫调节作用等健康益处而被用于传统医学. 本研究采用大鼠骨髓微核试验，对该组合及单独补品的遗传毒性致毒和预防能力进行了研究. For each experimental group five animals were used. A total of 2,000 polychromatic erythrocytes (PCE) were scored per animal. Data was analyzed by using a t-test. A significant decrease in the number of micronucleated cells was observed in the group that received the association and the individual supplements in combination with a genotoxic agent (p < .05), 提示个体补品对基因毒性制剂引起的遗传毒性有预防作用. However, 服用灵芝和冬虫夏草的组微核的形成也略有增加. Further studies to determine potential toxicity is recommended.